Nasal SprayFrom $166/mo
InjectionFrom $166/moNAD+ nasal spray
How the needle-free spray works, side effects and who it suits.
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Frequently asked questions
NAD+ Therapy Questions, Answered
Everything people ask us about NAD+ nasal spray and injections, from what NAD+ is to pricing, shipping and safety.
Medically reviewed by Vanessa Niles, R.N., M.D., F.A.C.O.G. —
Most asked
The NAD+ questions people ask most
Most people want to know the same few things before they start: whether NAD+ is FDA-approved, which form to choose, what it costs, how fast it arrives, whether insurance is needed and what side effects to expect.
Jump to a topic below, or book a free consultation to ask a licensed provider directly.
About NAD+
What is NAD+?
NAD+ (nicotinamide adenine dinucleotide) is a coenzyme found in every cell. It helps turn the food you eat into usable energy and is used by enzymes that maintain and repair DNA.
Why do people take NAD+?
Research shows NAD+ levels drop in several tissues as people age, so many people are interested in NAD+ as part of a healthy-aging routine. Whether taking it changes how you feel or age hasn't been proven.
Is NAD+ FDA-approved?
No. NAD+ has no FDA-approved use. The NAD+ prescribed through NADMedics is compounded by a licensed U.S. pharmacy, and compounded medicines are not FDA-approved or evaluated by the FDA for safety or effectiveness.
Is NAD+ the same as NMN or NR supplements?
No. NMN and NR are precursors your body converts into NAD+, and they're sold as supplements taken by mouth. NADMedics offers NAD+ itself, as a prescription nasal spray or injection.
How long does NAD+ take to work?
There's no reliable timeline because human research is limited. Some people describe changes within weeks and others notice none. Your provider checks in and helps you decide whether to continue.
Getting started
How do I get NAD+ through NADMedics?
Book a free online consultation and complete a short health questionnaire. A licensed U.S. provider reviews your history, and if NAD+ suits you, a licensed pharmacy ships it to your door.
Do I need a prescription?
Yes. Compounded NAD+ nasal spray and injections are prescription products. A provider decides at your consultation whether to prescribe.
Which is better, the spray or the injection?
Neither has been shown to work better. The spray is needle-free; the injection gives a measured dose under the skin. Pick the one that fits your comfort and routine, or ask your provider.
Who can't take NAD+?
NAD+ isn't prescribed during pregnancy or breastfeeding, to anyone under 18, or during active cancer treatment without the oncologist's agreement. Your provider may decline for other health reasons too.
Is care available in my state?
Book a free consultation and your provider will confirm whether NAD+ can be prescribed and shipped where you live before you pay anything.
Cost and billing
How much does NAD+ cost?
$199 for 1 month, $349 for 2 months or $499 for 3 months ($166/mo), for either the nasal spray or the injection. Prices are indicative and confirmed after eligibility. Your consultation is free and shipping is included.
Do you take insurance?
No. NADMedics is self-pay with one flat price, so there are no referrals, prior authorizations or surprise bills.
Can I cancel anytime?
Yes. There's no contract and no cancellation fee. Your plan stays active until the end of the period you've paid for.
Can I get a refund?
Dispensed medication can't be refunded for safety reasons, but damaged or incorrect orders reported within 7 days are replaced or refunded. See the Refund & Cancellation Policy for details.
Shipping and delivery
How long does delivery take?
Pharmacies usually prepare orders within 1 to 3 business days, and most arrive 2 to 5 business days after shipping.
Is the packaging discreet?
Yes. Orders arrive in plain packaging with nothing on the outside about what's inside.
How do I store NAD+?
Follow the storage instructions on your pharmacy label. NAD+ is often kept in the refrigerator, so bring your package inside promptly.
Safety and side effects
What side effects can NAD+ cause?
Commonly reported effects include flushing, headache, mild nausea and tiredness. The spray can irritate the nose; injections can cause redness or soreness where you inject.
What should I do if I have side effects?
Tell your provider. They can change your dose or schedule, or stop treatment. For chest pain or trouble breathing, call 911.
Can I take NAD+ with my other medicines?
Share every medicine and supplement at your consultation. Your provider checks for anything that makes NAD+ a poor fit before prescribing.
Still have a question? Email team@nadmedics.org or read the Refund & Cancellation Policy and Shipping Policy.
Keep reading
Learn more about NAD+ therapy
NAD+ injection
At-home shots under the skin: technique, storage and safety.
NAD+ therapy cost
What each plan includes and how billing works.
How it works
From free consultation to delivery, step by step.
NAD+ by state
Local details, shipping and license checks for all 50 states.
How we write
Our sourcing and review standards for health information.
Keep learning
In-depth NAD+ guides
Want more than a short answer? These guides go deeper, with official sources.
- How Much NAD+ Should I Inject? Dosage Made Simple for YouHow much NAD+ should you inject? There's no FDA-approved dose, so your provider sets it. Learn what shapes that dose, what studies used and how to measure it.NAD+ injections · 6 min read
- Are NAD+ Injections Safe? The Real Risks and Benefits SharedAre NAD+ injections safe? See the common side effects, what FDA alerts found about contaminated NAD+, who should avoid it and how to lower your risk.NAD+ injections · 6 min read
- How Often Should You Get NAD Injections? A Quick Time GuideHow often should you get NAD+ injections? Learn why schedules vary, what shapes how often your provider has you inject and why more often isn't always better.NAD+ injections · 4 min read
- NAD+ Nasal Spray Dosage: How Much Should You Really Use?How much NAD+ nasal spray should you use? Learn how sprays per day are set, how to work out mg per spray from your label and how to use the pump right.NAD+ nasal spray · 4 min read
- NAD+ Injections vs IV: Which Delivery Method Is Best for YouNAD+ injections vs IV drips: compare time, setting, cost, side effects and research, including what pilot studies found about IV NAD+. Not proven better.NAD+ injections · 5 min read
- Does Insurance Cover NAD Injections? What You Need to KnowDoes insurance cover NAD+ injections? Usually not. See why compounded NAD+ is rarely covered, what Medicare rules say and whether an HSA or FSA may help.Getting started · 4 min read
Official sources
NAD+ FAQ: sources and official resources
Official government and research sources behind this page, so you can check the facts yourself.
- NIH Office of Dietary SupplementsNiacin: Health Professional Fact Sheet
Explains how the body turns niacin (vitamin B3) into NAD, a coenzyme used by more than 400 enzymes.
- NIH PubMed CentralCovarrubias et al. NAD+ metabolism and its roles in cellular processes during ageing (2021)
Review of how NAD+ works in cells and how levels change with age.
- NIH PubMedNAD+ therapy in age-related degenerative disorders: a benefit/risk analysis (2020)
Weighs early promise against the lack of long-term human trials.
- U.S. Food and Drug AdministrationHuman Drug Compounding
FDA's hub on compounding, including that compounded drugs aren't FDA-reviewed for safety or effectiveness.
- U.S. Food and Drug AdministrationBeSafeRx: Your Source for Online Pharmacy Information
How to spot a legitimate online pharmacy and avoid unsafe sellers.
- U.S. Food and Drug AdministrationSafely Using Sharps (Needles and Syringes) at Home, at Work and on Travel
How to store and throw away used needles and syringes safely.
- U.S. Food and Drug AdministrationMedWatch: The FDA Safety Information and Adverse Event Reporting Program
Where patients can report side effects or problems with a medicine to the FDA.
- U.S. Department of Health and Human ServicesTelehealth for patients
Official guide to how telehealth visits work, what they cost and how to prepare.
The fastest way to get personal answers
Book a free consultation and a licensed provider will answer your questions about NAD+ directly.
Book a free consultation