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NAD+ injections

How Much NAD+ Should I Inject? Dosage Made Simple for You

It's the most common question we hear, and the honest answer starts with this: there's no standard NAD+ dose. Here's how providers decide, and how to make sure you inject exactly what's prescribed.

  • Read time6 min
  • UpdatedOctober 12, 2026
  • Sources6 official & research

Medically reviewed by Vanessa Niles, R.N., M.D., F.A.C.O.G. —

The short answer

Inject the dose your prescribing provider sets, measured exactly as your pharmacy label directs. NAD+ has no FDA-approved use, so there's no official dose; providers choose one based on your health, how you tolerate NAD+ and the product's strength.

  • There's no FDA-approved NAD+ dose for any use.
  • Your dose is set in milligrams; your syringe measures milliliters or units.
  • Study doses vary widely and were mostly given by IV, not under the skin.
  • Never change your dose without talking to your provider.

Why there's no standard dose

Doses come from clinical trials, and NAD+ injections haven't been through the large trials that set doses for approved medicines. NAD+ has no FDA-approved use, so there's no label dose to point to.

Instead, a licensed provider looks at your age, health, medicines and goals, and how you respond, and sets a dose and schedule for you.

What shapes your dose

Providers typically weigh:

  • Your health history, medicines and any conditions that call for caution
  • How you tolerate NAD+, especially flushing, nausea or chest tightness
  • The concentration of your vial, written as mg per mL
  • Whether you're new to NAD+ or continuing a plan
NADMedics · NAD+ injections
100 mgprescribed dose (example)
÷ 200 mg/mLvial strength
0.5 mLvolume to draw
50 unitson a U-100 syringe
FDA: mg, mL and units mix-ups have caused overdosesExample math only. Your provider sets your dose; check your label every time.
Prescribed mg ÷ vial strength (mg/mL) = mL to draw.

Dose math

Milligrams, milliliters and units

Your provider prescribes milligrams. Your vial's strength turns that into milliliters, and a U-100 syringe shows 100 units per milliliter. Getting this step right is what keeps your dose accurate.

What studies have used

Research doses aren't a recipe for home use, but they give context. A 2019 pilot study infused 750 mg of NAD+ by IV over six hours in healthy men. A small 2026 preprint gave 100 mg of NAD+ under the skin to six people. Oral precursor trials have used 250 to 1,000 mg a day of NMN or NR, which are different molecules.

Because these studies differ in route, length and molecule, none of them establishes a home injection dose.

Measuring your dose correctly

Your prescription is in milligrams (mg); your syringe is marked in milliliters (mL) or units. The FDA has warned that confusing mg, mL and units with compounded injections has led some patients to take 5 to 20 times the intended dose.

Divide your dose by the vial's strength to get mL. For example, 100 mg from a 200 mg/mL vial is 0.5 mL, which is 50 units on a U-100 syringe. Our dosage calculator does this math for you.

NAD+ terms used in this guide

Questions

Questions people also ask

Can I take more NAD+ to feel it faster?

No. Higher doses and faster injections are linked to more flushing, nausea and chest tightness, and there's no evidence more works better. Ask your provider before changing anything.

What if I miss a dose?

Follow your provider's instructions. Don't double up to make up for a missed shot unless they tell you to.

Is my dose based on body weight?

Not necessarily. There's no established weight-based formula for NAD+; your provider decides.

How many doses are in a 5 mL vial?

It depends on your dose. At 200 mg/mL the vial holds 1,000 mg, so a 100 mg dose would give about 10 doses. Use the dose calculator with your prescribed dose.

Will my provider start me on a lower dose?

Your provider decides. Doses are often adjusted over time based on how you tolerate NAD+ and how you feel.

What if my vial is a different strength?

Always use the strength printed on your own label to work out the volume, and ask your pharmacist if anything is unclear.

Keep reading

Related NAD+ guides

All NAD+ resources

Official sources

Sources and official resources

Official government and research sources behind this page, so you can check the facts yourself.

  1. U.S. Food and Drug AdministrationFDA alerts about dosing errors with compounded injectable products (2024)

    Mix-ups between milliliters, milligrams and syringe units led to overdoses.

  2. U.S. Food and Drug AdministrationDifferences in strength expression on compounded product labels may lead to dosing errors

    Why reading mg per mL correctly matters.

  3. Frontiers in Aging NeuroscienceGrant et al. Changes in the human NAD+ metabolome during a 6-hour NAD+ infusion (2019)

    Small pilot study of intravenous NAD+ in healthy adults.

  4. medRxiv (preprint, not peer reviewed)Nkrumah-Elie et al. Preliminary safety analysis of two pilot clinical trials involving injections of nicotinamide riboside (2026)

    Pilot trial that included a small subcutaneous NAD+ group; early safety data only.

  5. GeroScienceYi et al. The efficacy and safety of NMN supplementation in healthy middle-aged adults (2023)

    60-day randomized trial of 300, 600 and 900 mg/day oral NMN.

  6. U.S. Food and Drug AdministrationCompounding and the FDA: Questions and Answers

    What compounded medicines are and why they aren't FDA-approved.

Medically reviewed by Dr. Vanessa Niles, R.N., M.D., F.A.C.O.G., on October 12, 2026. This article is general education, not medical advice. NAD+ has no FDA-approved use, and compounded NAD+ is not FDA-approved or evaluated by the FDA for safety or effectiveness. Only your provider can set your dose.

Talk it through with a provider

Book a free online consultation. If NAD+ fits, a licensed U.S. provider prescribes the nasal spray or injection, with plans from $166 a month.

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