A measured dose
Each shot delivers the amount your provider prescribes, drawn from a vial with a small, fine needle.
At-home NAD+ shots
A small shot under the skin on the schedule your provider sets, no clinic visit needed. Start with a free online consultation; if a licensed U.S. provider decides NAD+ fits, your vials and supplies ship to you with clear instructions.

Medically reviewed by Vanessa Niles, R.N., M.D., F.A.C.O.G. —
Why this form
Each shot delivers the amount your provider prescribes, drawn from a vial with a small, fine needle.
Many clinics give NAD+ through an IV over hours. A shot under the skin takes a minute in your own home.
Your provider explains the technique and your package includes step-by-step instructions, so you're never guessing.

At-home injections
Your NAD+ injection routine comes down to four things: the vial your pharmacy prepares, a fresh syringe for each dose, a sharps container for used needles and the schedule your provider sets.
Compare
Neither form has been shown to work better. The right one is the one that fits your comfort and routine.
| NAD+ nasal spray | NAD+ injection | |
|---|---|---|
| How it's taken | Sprayed into the nose | Small shot just under the skin |
| Needles | None | A small, fine needle |
| Time per dose | A few seconds | About a minute |
| How often | Usually daily, as directed | On the schedule your provider sets |
| Common side effects | Nose irritation, headache, flushing | Injection-site soreness, flushing, nausea |
| Storage | As labeled, often refrigerated | As labeled, often refrigerated |
| Best for | People who prefer no needles | People who want a measured dose |
| Strength | 30 mg per 0.1 mL · 15 mL bottle | 200 mg/mL · 5 mL vial |
| Price | From $166 a month | From $166 a month |
| FDA status | No FDA-approved use; compounded | No FDA-approved use; compounded |
Your routine
Your provider sets the dose, the schedule and the sites. Here's the general flow, so you know what to expect.
Wash your hands, wipe the vial top and the skin with alcohol, and let them dry.
Draw the prescribed amount into the syringe, exactly as the label and your provider describe.
Pinch a fold of skin on the belly or thigh, insert the needle and press the plunger slowly. Going slower often means less flushing.
Use a different spot each time and put used needles straight into a sharps container.
Storage and safety
Bring the package inside promptly and store it exactly as the pharmacy label says. NAD+ is often kept in the refrigerator, away from the freezer.
Don't leave vials in a hot car or in direct sun. If you travel, ask your provider how to carry them.
Put used needles straight into an FDA-cleared sharps container, never loose in the trash, and follow your local disposal rules.
FDA: safely using and disposing of sharps ↗Don't keep using it past the date on the label. Use a drug take-back site or the FDA's at-home disposal steps.
FDA: disposal of unused medicines ↗Getting started
Choose a time and fill in a short health form. Talking with a provider costs nothing.
A licensed U.S. provider goes over your history and medicines and tells you whether NAD+ injection is a good fit.
If prescribed, a licensed pharmacy ships it to you, and your care team checks in on how it’s going.
The evidence
NAD+ is a coenzyme found in every cell. It helps turn food into usable energy and fuels enzymes that look after your DNA. Research shows levels drop in several tissues with age.
Scientists are studying whether restoring NAD+ affects aging and metabolism. A small 2019 pilot study gave NAD+ by IV with no adverse events reported, but injections under the skin have very little published research.
It has not been shown to reverse aging or improve energy, mood or focus. NAD+ has no FDA-approved use, and compounded NAD+ injections are not FDA-approved or FDA-reviewed.
Safety
Your provider reviews your health and medicines first, and you can report anything along the way.
Buy safely
Four checks the FDA and pharmacy regulators recommend before buying prescription medicine online.
Real NAD+ therapy needs a prescription. Be wary of any site that sells it without a health review.
Compounded NAD+ should come from a state-licensed pharmacy, never an anonymous overseas seller.
FDA BeSafeRx: spot a safe online pharmacy ↗Look up any online pharmacy before you buy to confirm it's legitimate and licensed.
Verify a pharmacy at Safe.Pharmacy (NABP) ↗Healthcare sites certified by LegitScript have been checked against legal and safety standards.
See the LegitScript lookup for NADMedics ↗Product details
NAD+ supports cellular energy, DNA repair and overall metabolic function, and it’s widely studied for healthy aging and longevity. Here’s exactly what you receive if a physician prescribes it.

For example, a 100 mg dose is 0.5 mL, or 50 units on a U-100 syringe. Your provider sets your dose.
Pricing
Indicative price · confirmed after eligibility · prescription treatment
Prescription treatment — available only to eligible patients after clinical evaluation.
NAD+ injection, if prescribed. No insurance needed.
The consultation is free and you pay only if a provider prescribes. NAD+ has no FDA-approved use; compounded NAD+ is not FDA-approved.

Rather skip needles? The nasal spray is a daily, needle-free option at the same price.
Your physicians
Board-certified physicians with decades of practice oversee NADMedics care. A licensed provider makes every prescribing decision.

R.N., M.D., F.A.C.O.G.
Obstetrics & gynecologyA board-certified OB-GYN with more than 40 years in practice, known for treating the whole person rather than a single symptom.

M.D.
Metabolic health & longevityBoard certified in anesthesiology, a specialty built on how drugs move through the body. He applies that precision to dosing and monitoring NAD+ care.
By state
Consultations are online and NAD+ ships to your door. Find your state for local details.
Questions
Yes. These are subcutaneous shots, given just under the skin with a small needle, much like many other home injections. Your provider explains the technique and your package includes written steps.
$199 for 1 month, $349 for 2 months or $499 for 3 months ($166/mo). Prices are indicative and confirmed after eligibility. The consultation is free, you don't need insurance, and you pay only if a provider prescribes.
An IV drip runs NAD+ straight into the bloodstream, usually over hours in a clinic chair. A subcutaneous shot takes a minute at home. The two haven't been compared head to head, and neither is FDA-approved for any use.
Flushing and a warm or tight feeling are commonly reported with NAD+, especially when it's given quickly. Injecting more slowly often helps; tell your provider if it bothers you.
There's no FDA-approved dose, because NAD+ has no approved use. Your provider sets a dose and schedule for you and adjusts it based on how you respond.
No. Compounded NAD+ is prepared by a licensed U.S. pharmacy under a prescription, but the FDA doesn't evaluate compounded medicines for safety or effectiveness.
Try the NAD+ nasal spray instead: no needles, same price. Your provider can help you choose.
Keep learning
Straight answers on dosing, safety, storage and getting started, each reviewed by a physician.
Official sources
Official government and research sources behind this page, so you can check the facts yourself.
Explains how the body turns niacin (vitamin B3) into NAD, a coenzyme used by more than 400 enzymes.
Review of how NAD+ works in cells and how levels change with age.
Weighs early promise against the lack of long-term human trials.
Small pilot study of intravenous NAD+ in healthy adults.
FDA's hub on compounding, including that compounded drugs aren't FDA-reviewed for safety or effectiveness.
What compounded medicines are and why they aren't FDA-approved.
How to spot a legitimate online pharmacy and avoid unsafe sellers.
How to store and throw away used needles and syringes safely.
Where patients can report side effects or problems with a medicine to the FDA.
Official guide to how telehealth visits work, what they cost and how to prepare.
Medically reviewed by Dr. Vanessa Niles, R.N., M.D., F.A.C.O.G., on October 12, 2026. This page is general education, not medical advice. NAD+ has no FDA-approved use; compounded NAD+ injection is not FDA-approved and the FDA hasn’t evaluated it for safety or effectiveness. A licensed provider must look over your health and approve it before it’s prescribed, and experiences differ from person to person.
Book a free online consultation. A licensed provider will tell you honestly whether it suits you.
Book a free consultation