1. Home
  2. NAD+ injection

At-home NAD+ shots

NAD+ injections, done at home

A small shot under the skin on the schedule your provider sets, no clinic visit needed. Start with a free online consultation; if a licensed U.S. provider decides NAD+ fits, your vials and supplies ship to you with clear instructions.

  • Licensed U.S. providers
  • Pay only if prescribed
  • Ships discreetly
NADMedics NAD+ injection vial
InjectionCompounded NAD+
From $166/moFree consultation

Medically reviewed by Vanessa Niles, R.N., M.D., F.A.C.O.G. —

Why this form

Why choose NAD+ injection?

A measured dose

Each shot delivers the amount your provider prescribes, drawn from a vial with a small, fine needle.

No IV chair

Many clinics give NAD+ through an IV over hours. A shot under the skin takes a minute in your own home.

Guided the first time

Your provider explains the technique and your package includes step-by-step instructions, so you're never guessing.

Illustration of an NADMedics NAD+ injection vial, a syringe, a red sharps container and a dosing calendar
An NAD+ vial, a fresh syringe, a sharps container and your provider's schedule.

At-home injections

What you need for at-home NAD+ injections

Your NAD+ injection routine comes down to four things: the vial your pharmacy prepares, a fresh syringe for each dose, a sharps container for used needles and the schedule your provider sets.

  • A new needle and a new spot every time
  • Used needles go straight into a sharps container
  • Doses follow your provider’s schedule, not guesswork
FDA guidance on using and disposing of sharps ↗

Compare

NAD+ injection vs. NAD+ nasal spray: how they compare

Neither form has been shown to work better. The right one is the one that fits your comfort and routine.

NAD+ nasal spray compared with NAD+ injection
NAD+ nasal sprayNAD+ injection
How it's takenSprayed into the noseSmall shot just under the skin
NeedlesNoneA small, fine needle
Time per doseA few secondsAbout a minute
How oftenUsually daily, as directedOn the schedule your provider sets
Common side effectsNose irritation, headache, flushingInjection-site soreness, flushing, nausea
StorageAs labeled, often refrigeratedAs labeled, often refrigerated
Best forPeople who prefer no needlesPeople who want a measured dose
Strength30 mg per 0.1 mL · 15 mL bottle200 mg/mL · 5 mL vial
PriceFrom $166 a monthFrom $166 a month
FDA statusNo FDA-approved use; compoundedNo FDA-approved use; compounded

Your routine

What a shot day looks like

Your provider sets the dose, the schedule and the sites. Here's the general flow, so you know what to expect.

Keep vials as the label says. NAD+ vials are commonly stored in the refrigerator.
  1. 1

    Set up clean

    Wash your hands, wipe the vial top and the skin with alcohol, and let them dry.

  2. 2

    Draw your dose

    Draw the prescribed amount into the syringe, exactly as the label and your provider describe.

  3. 3

    Inject slowly

    Pinch a fold of skin on the belly or thigh, insert the needle and press the plunger slowly. Going slower often means less flushing.

  4. 4

    Rotate and dispose

    Use a different spot each time and put used needles straight into a sharps container.

Storage and safety

How to store NAD+ injection vials and dispose of it safely

When it arrives

Bring the package inside promptly and store it exactly as the pharmacy label says. NAD+ is often kept in the refrigerator, away from the freezer.

Keep it away from heat

Don't leave vials in a hot car or in direct sun. If you travel, ask your provider how to carry them.

Getting started

How to get NAD+ injection online in three steps

  1. 1

    Book your free visit

    Choose a time and fill in a short health form. Talking with a provider costs nothing.

  2. 2

    Provider review

    A licensed U.S. provider goes over your history and medicines and tells you whether NAD+ injection is a good fit.

  3. 3

    Delivered with instructions

    If prescribed, a licensed pharmacy ships it to you, and your care team checks in on how it’s going.

The evidence

Does NAD+ injection work? What the evidence says

Known

NAD+ is a coenzyme found in every cell. It helps turn food into usable energy and fuels enzymes that look after your DNA. Research shows levels drop in several tissues with age.

Being studied

Scientists are studying whether restoring NAD+ affects aging and metabolism. A small 2019 pilot study gave NAD+ by IV with no adverse events reported, but injections under the skin have very little published research.

Not proven

It has not been shown to reverse aging or improve energy, mood or focus. NAD+ has no FDA-approved use, and compounded NAD+ injections are not FDA-approved or FDA-reviewed.

Safety

NAD+ injection side effects and who should skip it

Your provider reviews your health and medicines first, and you can report anything along the way.

Commonly reported

  • Redness, soreness or a small bump where you injected
  • Flushing or a warm feeling
  • A tight or heavy feeling in the chest or stomach during the dose
  • Nausea or headache
  • Feeling tired afterward

Contact your provider

  • Chest pain or trouble breathing (call 911)
  • Spreading redness, warmth or pus at an injection site
  • Side effects that last beyond the day of your dose

Not prescribed for

  • Pregnancy or breastfeeding, since safety hasn't been studied
  • Active cancer treatment, unless your oncologist agrees
  • Anyone under 18
  • People who can't safely give themselves injections

Buy safely

How to buy NAD+ injection online safely

Four checks the FDA and pharmacy regulators recommend before buying prescription medicine online.

A licensed provider reviews you first

Real NAD+ therapy needs a prescription. Be wary of any site that sells it without a health review.

Product details

NAD+ injection: strength and package

NAD+ supports cellular energy, DNA repair and overall metabolic function, and it’s widely studied for healthy aging and longevity. Here’s exactly what you receive if a physician prescribes it.

NADMedics NAD+ injection vial

NAD+ injection

Strength
200 mg per mL
Package
5 mL vial
Total NAD+
1,000 mg of NAD+ per vial

For example, a 100 mg dose is 0.5 mL, or 50 units on a U-100 syringe. Your provider sets your dose.

Pricing

NAD+ injection cost

  • 1 month$199$199/mo
  • 2 months$349$174.50/mo
  • Best value3 months$499$166/mo

Indicative price · confirmed after eligibility · prescription treatment

Prescription treatment — available only to eligible patients after clinical evaluation.

NAD+ injection, if prescribed. No insurance needed.

  • NAD+ nasal spray
  • NAD+ injection

What your plan includes

  • Free online consultation
  • 1 visit with a licensed physician
  • Up to a 6-month supply of medication, as prescribed
  • Provider review of your health history and medicines
  • NAD+ compounded for you by a licensed U.S. pharmacy, when prescribed
  • Discreet delivery to your door
  • Follow-up with your care team as you go

The consultation is free and you pay only if a provider prescribes. NAD+ has no FDA-approved use; compounded NAD+ is not FDA-approved.

NADMedics NAD+ nasal spray bottle

Prefer the nasal spray?

Rather skip needles? The nasal spray is a daily, needle-free option at the same price.

See NAD+ nasal spray

Your physicians

The physicians behind your NAD+ injection

Board-certified physicians with decades of practice oversee NADMedics care. A licensed provider makes every prescribing decision.

Dr. Vanessa Niles, R.N., M.D., F.A.C.O.G.

Dr. Vanessa Niles

R.N., M.D., F.A.C.O.G.

Obstetrics & gynecology

A board-certified OB-GYN with more than 40 years in practice, known for treating the whole person rather than a single symptom.

  • M.D., Meharry Medical College
  • Residency, Brookdale University Hospital and Medical Center
  • Board certified in OB-GYN · Fellow, ACOG
Dr. Benjamin H. Krasne, M.D.

Dr. Benjamin H. Krasne

M.D.

Metabolic health & longevity

Board certified in anesthesiology, a specialty built on how drugs move through the body. He applies that precision to dosing and monitoring NAD+ care.

  • M.D., University of Miami Miller School of Medicine
  • Residency, Jackson Memorial Hospital
  • Board certified, American Board of Anesthesiology

Questions

NAD+ injection: common questions

Can I really do NAD+ injections at home?

Yes. These are subcutaneous shots, given just under the skin with a small needle, much like many other home injections. Your provider explains the technique and your package includes written steps.

How much do NAD+ injections cost?

$199 for 1 month, $349 for 2 months or $499 for 3 months ($166/mo). Prices are indicative and confirmed after eligibility. The consultation is free, you don't need insurance, and you pay only if a provider prescribes.

How is this different from an NAD+ IV drip?

An IV drip runs NAD+ straight into the bloodstream, usually over hours in a clinic chair. A subcutaneous shot takes a minute at home. The two haven't been compared head to head, and neither is FDA-approved for any use.

Why do I feel flushed after a shot?

Flushing and a warm or tight feeling are commonly reported with NAD+, especially when it's given quickly. Injecting more slowly often helps; tell your provider if it bothers you.

What dose will I get?

There's no FDA-approved dose, because NAD+ has no approved use. Your provider sets a dose and schedule for you and adjusts it based on how you respond.

Are NAD+ injections FDA-approved?

No. Compounded NAD+ is prepared by a licensed U.S. pharmacy under a prescription, but the FDA doesn't evaluate compounded medicines for safety or effectiveness.

What if I don't like needles?

Try the NAD+ nasal spray instead: no needles, same price. Your provider can help you choose.

Keep learning

NAD+ injection guides

Straight answers on dosing, safety, storage and getting started, each reviewed by a physician.

All NAD+ guides NAD+ glossary

Official sources

NAD+ injection: sources and official resources

Official government and research sources behind this page, so you can check the facts yourself.

  1. NIH Office of Dietary SupplementsNiacin: Health Professional Fact Sheet

    Explains how the body turns niacin (vitamin B3) into NAD, a coenzyme used by more than 400 enzymes.

  2. NIH PubMed CentralCovarrubias et al. NAD+ metabolism and its roles in cellular processes during ageing (2021)

    Review of how NAD+ works in cells and how levels change with age.

  3. NIH PubMedNAD+ therapy in age-related degenerative disorders: a benefit/risk analysis (2020)

    Weighs early promise against the lack of long-term human trials.

  4. Frontiers in Aging NeuroscienceGrant et al. Changes in the human NAD+ metabolome during a 6-hour NAD+ infusion (2019)

    Small pilot study of intravenous NAD+ in healthy adults.

  5. U.S. Food and Drug AdministrationHuman Drug Compounding

    FDA's hub on compounding, including that compounded drugs aren't FDA-reviewed for safety or effectiveness.

  6. U.S. Food and Drug AdministrationCompounding and the FDA: Questions and Answers

    What compounded medicines are and why they aren't FDA-approved.

  7. U.S. Food and Drug AdministrationBeSafeRx: Your Source for Online Pharmacy Information

    How to spot a legitimate online pharmacy and avoid unsafe sellers.

  8. U.S. Food and Drug AdministrationSafely Using Sharps (Needles and Syringes) at Home, at Work and on Travel

    How to store and throw away used needles and syringes safely.

  9. U.S. Food and Drug AdministrationMedWatch: The FDA Safety Information and Adverse Event Reporting Program

    Where patients can report side effects or problems with a medicine to the FDA.

  10. U.S. Department of Health and Human ServicesTelehealth for patients

    Official guide to how telehealth visits work, what they cost and how to prepare.

Medically reviewed by Dr. Vanessa Niles, R.N., M.D., F.A.C.O.G., on October 12, 2026. This page is general education, not medical advice. NAD+ has no FDA-approved use; compounded NAD+ injection is not FDA-approved and the FDA hasn’t evaluated it for safety or effectiveness. A licensed provider must look over your health and approve it before it’s prescribed, and experiences differ from person to person.

Ready to ask about NAD+ injection?

Book a free online consultation. A licensed provider will tell you honestly whether it suits you.

Book a free consultation