Nasal SprayFrom $166/mo
InjectionFrom $166/mo
Medically reviewed by Vanessa Niles, R.N., M.D., F.A.C.O.G. —
The short answer
An NAD+ injection is a prescription shot of compounded nicotinamide adenine dinucleotide (NAD+), a coenzyme found in every cell. At NADMedics it's a subcutaneous shot you give yourself at home on the schedule your provider sets. NAD+ has no FDA-approved use, and research on injections is still very limited.
- NAD+ is a coenzyme more than 400 enzymes need, according to NIH.
- Home NAD+ injections go into the fat just under the skin, not into a vein.
- Compounded NAD+ isn't FDA-approved, so a licensed provider and pharmacy matter.
- At NADMedics: $199 for 1 month, $349 for 2 or $499 for 3 months ($166/mo).
What NAD+ is, in one minute
NAD+ (nicotinamide adenine dinucleotide) is a helper molecule your cells use to turn food into energy and to run enzymes involved in DNA repair. NIH's Office of Dietary Supplements notes that more than 400 enzymes need NAD to work.
Your body builds NAD+ from forms of vitamin B3 and from the amino acid tryptophan. Research reviews describe NAD+ levels falling in several tissues as people age, which is why it gets so much attention.
What an NAD+ injection actually is
An NAD+ injection delivers NAD+ itself, rather than a vitamin the body has to convert. The at-home version is subcutaneous: a short, thin needle places the dose in the fatty layer under the skin of the belly or thigh, as MedlinePlus describes for any subcutaneous shot.
The NAD+ is compounded, meaning a licensed pharmacy prepares it for you under a prescription. The FDA doesn't review compounded drugs for safety or effectiveness before they're dispensed. NAD+ is currently listed by the FDA as a bulk substance under evaluation for 503A compounding.
At a glance
From consultation to your first shot
A licensed provider reviews your health at a free online visit. If NAD+ fits, a licensed pharmacy compounds it, it ships cold to your door, and your provider shows you the technique.
What the research says so far
Most human NAD+ research uses oral precursors such as nicotinamide riboside (NR) and NMN, which raise blood NAD+ levels in small trials. Studies of NAD+ itself are fewer: a 2019 pilot study gave NAD+ by IV, and a small 2026 preprint included a subcutaneous NAD+ group.
None of this shows that NAD+ injections slow aging, boost energy or sharpen focus. Anyone who tells you otherwise is getting ahead of the evidence.
Who should skip NAD+ injections
NADMedics providers don't prescribe NAD+ in these situations:
- Pregnancy or breastfeeding, since safety hasn't been studied
- Anyone under 18
- Active cancer treatment, unless your oncologist agrees
- Anyone who can't safely give themselves injections
Questions
Questions people also ask
Is NAD the same as NAD+?
People use them interchangeably. Strictly, NAD+ is the oxidized form of NAD, and it's what's in compounded NAD+ injections.
Do NAD+ injections hurt?
Most people feel a quick pinch. Some notice warmth, flushing or a heavy feeling during the dose; injecting more slowly often helps.
Are NAD+ injections FDA-approved?
No. NAD+ has no FDA-approved use, and compounded NAD+ isn't FDA-approved or FDA-reviewed.
How much do NAD+ injections cost at NADMedics?
$199 for 1 month, $349 for 2 months or $499 for 3 months ($166/mo). Prices are indicative and confirmed after eligibility, and every plan includes 1 visit with a licensed physician.
What strength are NADMedics NAD+ injections?
200 mg per mL in a 5 mL vial, which is 1,000 mg of NAD+ in all. Your provider sets how much you inject.
Where on the body are NAD+ injections given?
Into the fatty layer just under the skin, usually the belly or thigh. Rotate to a new spot each time, at least an inch from the last one.
Keep reading
Related NAD+ guides
- How to Get NAD Injections: Your Easy Start-to-Finish RoadmapHow to get NAD+ injections legally and safely: book a free online consultation, get a provider review and prescription, and have NAD+ shipped by a pharmacy.Getting started
- Are NAD+ Injections Safe? The Real Risks and Benefits SharedAre NAD+ injections safe? See the common side effects, what FDA alerts found about contaminated NAD+, who should avoid it and how to lower your risk.NAD+ injections
- How to Inject NAD+: A Safe Step-by-Step Guide for BeginnersHow to inject NAD+ at home: prepare, draw your dose from the vial, inject under the skin, rotate sites and dispose of needles safely. A beginner's guide.NAD+ injections
Official sources
Sources and official resources
Official government and research sources behind this page, so you can check the facts yourself.
- NIH Office of Dietary SupplementsNiacin: Health Professional Fact Sheet
Explains how the body turns niacin (vitamin B3) into NAD, a coenzyme used by more than 400 enzymes.
- MedlinePlus (National Library of Medicine)Subcutaneous (SQ) injections
Step-by-step guide to giving a shot into the fatty tissue under the skin.
- U.S. Food and Drug AdministrationCompounding and the FDA: Questions and Answers
What compounded medicines are and why they aren't FDA-approved.
- U.S. Food and Drug AdministrationBulk Drug Substances Nominated for Use in Compounding Under Section 503A
FDA's list showing NAD and NADH in Category 1, bulk substances under evaluation.
- NIH PubMed CentralCovarrubias et al. NAD+ metabolism and its roles in cellular processes during ageing (2021)
Review of how NAD+ works in cells and how levels change with age.
- Frontiers in Aging NeuroscienceGrant et al. Changes in the human NAD+ metabolome during a 6-hour NAD+ infusion (2019)
Small pilot study of intravenous NAD+ in healthy adults.
Medically reviewed by Dr. Vanessa Niles, R.N., M.D., F.A.C.O.G., on October 12, 2026. This article is general education, not medical advice. NAD+ has no FDA-approved use, and compounded NAD+ is not FDA-approved or evaluated by the FDA for safety or effectiveness. Only your provider can set your dose.
Talk it through with a provider
Book a free online consultation. If NAD+ fits, a licensed U.S. provider prescribes the nasal spray or injection, with plans from $166 a month.
Book a free consultation