Fits a busy morning
A couple of sprays takes seconds, so it slips into the routine you already have, at home or on the road.
- Home
- NAD+ nasal spray
Needle-free NAD+
NAD+ nasal spray, prescribed online
A few sprays a day, no needles. Book a free online consultation and a licensed U.S. provider looks at your health history to decide whether compounded NAD+ nasal spray makes sense for you. If it does, it ships to your door.
- Licensed U.S. providers
- Pay only if prescribed
- Ships discreetly
Nasal sprayCompounded NAD+
From $166/moFree consultation
- Strength30 mg per 0.1 mL
- How oftenDaily, as your provider directs
- NeedlesNone
- PriceFrom $166/mo
Medically reviewed by Vanessa Niles, R.N., M.D., F.A.C.O.G. —
Why this form
Why choose NAD+ nasal spray?
For people who avoid needles
If shots are a deal-breaker, the spray is the gentler way to try NAD+ under a provider's care.
Easy to pause or adjust
Your provider can change how many sprays you use or when you take them as you report back on how you feel.
Needle-free
A needle-free NAD+ routine in a few seconds
NAD+ nasal spray is built for busy days: ready the pump, clear your nose, spray and breathe softly, then store the bottle as labeled. It fits beside the rest of your morning routine.
- No needles and no sharps to dispose of
- Takes a few seconds a day
- Easy to adjust with your provider
Compare
NAD+ nasal spray vs. NAD+ injection: how they compare
Neither form has been shown to work better. The right one is the one that fits your comfort and routine.
| NAD+ nasal spray | NAD+ injection | |
|---|---|---|
| How it's taken | Sprayed into the nose | Small shot just under the skin |
| Needles | None | A small, fine needle |
| Time per dose | A few seconds | About a minute |
| How often | Usually daily, as directed | On the schedule your provider sets |
| Common side effects | Nose irritation, headache, flushing | Injection-site soreness, flushing, nausea |
| Storage | As labeled, often refrigerated | As labeled, often refrigerated |
| Best for | People who prefer no needles | People who want a measured dose |
| Strength | 30 mg per 0.1 mL · 15 mL bottle | 200 mg/mL · 5 mL vial |
| Price | From $166 a month | From $166 a month |
| FDA status | No FDA-approved use; compounded | No FDA-approved use; compounded |
Your routine
Using the spray, start to finish
Your pharmacy label and provider set the exact dose. This is the general rhythm most people follow.
If evening doses keep you awake, ask your provider about moving them to the morning.
- 1
Ready the pump
Before the first use, spray into the air a few times until a fine mist comes out, as the label describes.
- 2
Clear your nose
Blow your nose gently so the mist reaches the lining instead of running back out.
- 3
Spray and breathe softly
Tip your head slightly forward, spray into one nostril and breathe in gently. A hard sniff sends it down your throat.
- 4
Store it as labeled
Keep the cap on and follow the storage line on the label. Many NAD+ products live in the refrigerator.
Storage and safety
How to store NAD+ nasal spray and dispose of it safely
When it arrives
Bring the package inside promptly and store it exactly as the pharmacy label says. NAD+ is often kept in the refrigerator, away from the freezer.
Keep it away from heat
Don't leave the bottle in a hot car or on a sunny windowsill, and keep the cap on between doses.
Keep the tip clean
Wipe the nozzle with a clean tissue after use and don't share the bottle with anyone.
Leftover or expired NAD+
Don't keep using it past the date on the label. Use a drug take-back site or the FDA's at-home disposal steps.
FDA: disposal of unused medicines ↗Getting started
How to get NAD+ nasal spray online in three steps
- 1
Book your free visit
Choose a time and fill in a short health form. Talking with a provider costs nothing.
- 2
Provider review
A licensed U.S. provider goes over your history and medicines and tells you whether NAD+ nasal spray is a good fit.
- 3
Delivered with instructions
If prescribed, a licensed pharmacy ships it to you, and your care team checks in on how it’s going.
The evidence
Does NAD+ nasal spray work? What the evidence says
NAD+ is a coenzyme in every cell. It carries energy from the food you eat and is used by enzymes that help repair DNA. Studies show levels fall in several tissues as people age.
Researchers are testing whether raising NAD+ affects aging, energy and metabolism. Most human trials use precursors taken by mouth; studies of NAD+ given through the nose are few and small.
It has not been shown to slow aging, boost energy or sharpen focus. NAD+ has no FDA-approved use, and compounded NAD+ nasal spray is not FDA-approved or FDA-reviewed.
Safety
NAD+ nasal spray side effects and who should skip it
Your provider reviews your health and medicines first, and you can report anything along the way.
Commonly reported
- Stinging, dryness or irritation inside the nose
- Sneezing, a runny or a stuffy nose
- Headache
- Warmth or flushing of the face
- Mild nausea
Contact your provider
- Nosebleeds that keep coming back
- Symptoms that get worse instead of settling after the first week
- Any reaction that worries you
Not prescribed for
- Pregnancy or breastfeeding, since safety hasn't been studied
- Active cancer treatment, unless your oncologist agrees
- Anyone under 18
- Serious medical conditions your provider believes make it unsuitable
Buy safely
How to buy NAD+ nasal spray online safely
Four checks the FDA and pharmacy regulators recommend before buying prescription medicine online.
A licensed provider reviews you first
Real NAD+ therapy needs a prescription. Be wary of any site that sells it without a health review.
A licensed U.S. pharmacy fills it
Compounded NAD+ should come from a state-licensed pharmacy, never an anonymous overseas seller.
FDA BeSafeRx: spot a safe online pharmacy ↗The pharmacy can be verified
Look up any online pharmacy before you buy to confirm it's legitimate and licensed.
Verify a pharmacy at Safe.Pharmacy (NABP) ↗The website is independently certified
Healthcare sites certified by LegitScript have been checked against legal and safety standards.
See the LegitScript lookup for NADMedics ↗Product details
NAD+ nasal spray: strength and package
NAD+ supports cellular energy, DNA repair and overall metabolic function, and it’s widely studied for healthy aging and longevity. Here’s exactly what you receive if a physician prescribes it.
NAD+ nasal spray
- Strength
- 30 mg per 0.1 mL
- Package
- 15 mL bottle
- Total NAD+
- 4,500 mg of NAD+ per bottle
If your pump delivers 0.1 mL per spray, each spray contains 30 mg. Your provider sets how many sprays you use.
Pricing
NAD+ nasal spray cost
- 1 month$199$199/mo
- 2 months$349$174.50/mo
- Best value3 months$499$166/mo
Indicative price · confirmed after eligibility · prescription treatment
Prescription treatment — available only to eligible patients after clinical evaluation.
NAD+ nasal spray, if prescribed. No insurance needed.
- NAD+ nasal spray
- NAD+ injection
What your plan includes
- Free online consultation
- 1 visit with a licensed physician
- Up to a 6-month supply of medication, as prescribed
- Provider review of your health history and medicines
- NAD+ compounded for you by a licensed U.S. pharmacy, when prescribed
- Discreet delivery to your door
- Follow-up with your care team as you go
The consultation is free and you pay only if a provider prescribes. NAD+ has no FDA-approved use; compounded NAD+ is not FDA-approved.
Prefer the injection?
Comfortable with a small needle? The injection gives a measured dose under the skin.
Your physicians
The physicians behind your NAD+ nasal spray
Board-certified physicians with decades of practice oversee NADMedics care. A licensed provider makes every prescribing decision.
Dr. Vanessa Niles
R.N., M.D., F.A.C.O.G.
Obstetrics & gynecologyA board-certified OB-GYN with more than 40 years in practice, known for treating the whole person rather than a single symptom.
- M.D., Meharry Medical College
- Residency, Brookdale University Hospital and Medical Center
- Board certified in OB-GYN · Fellow, ACOG
Dr. Benjamin H. Krasne
M.D.
Metabolic health & longevityBoard certified in anesthesiology, a specialty built on how drugs move through the body. He applies that precision to dosing and monitoring NAD+ care.
- M.D., University of Miami Miller School of Medicine
- Residency, Jackson Memorial Hospital
- Board certified, American Board of Anesthesiology
By state
NAD+ nasal spray by state
Consultations are online and NAD+ ships to your door. Find your state for local details.
- Alabama
- Alaska
- Arizona
- Arkansas
- California
- Colorado
- Connecticut
- Delaware
- Florida
- Georgia
- Hawaii
- Idaho
- Illinois
- Indiana
- Iowa
- Kansas
- Kentucky
- Louisiana
- Maine
- Maryland
- Massachusetts
- Michigan
- Minnesota
- Mississippi
- Missouri
- Montana
- Nebraska
- Nevada
- New Hampshire
- New Jersey
- New Mexico
- New York
- North Carolina
- North Dakota
- Ohio
- Oklahoma
- Oregon
- Pennsylvania
- Rhode Island
- South Carolina
- South Dakota
- Tennessee
- Texas
- Utah
- Vermont
- Virginia
- Washington
- West Virginia
- Wisconsin
- Wyoming
Questions
NAD+ nasal spray: common questions
Do I need a prescription for NAD+ nasal spray?
Yes. Compounded NAD+ nasal spray is a prescription product. Through NADMedics, a licensed provider reviews your history at a free online consultation and prescribes it only if it suits you.
How much does NAD+ nasal spray cost?
$199 for 1 month, $349 for 2 months or $499 for 3 months ($166/mo). Prices are indicative and confirmed after eligibility. Talking with a provider costs nothing, you don't need insurance, and you're charged only if it's prescribed.
Is the spray FDA-approved?
No. NAD+ has no FDA-approved use, and the FDA doesn't check compounded medicines for safety or effectiveness before they're dispensed. A licensed U.S. pharmacy prepares it for you under a prescription.
How soon would I notice anything?
There's no reliable timeline, because the research is limited. Some people describe changes within weeks and others notice nothing. Your provider checks in and helps you decide whether to continue.
Spray or injection: which is better?
Neither has been shown to be better. The spray avoids needles; the injection delivers a measured dose under the skin. Your provider can talk through which suits your routine and comfort.
Does NAD+ nasal spray burn?
A brief sting or tingle is common at first and often eases with time. Tell your provider if it doesn't, or if your nose stays irritated.
Can I use it with my other medicines?
Share every medicine and supplement at your consultation. Your provider checks for anything that makes NAD+ a poor fit before prescribing.
Keep learning
NAD+ nasal spray guides
Straight answers on dosing, safety, storage and getting started, each reviewed by a physician.
- NAD+ Nasal Spray Dosage: How Much Should You Really Use?How much NAD+ nasal spray should you use? Learn how sprays per day are set, how to work out mg per spray from your label and how to use the pump right.NAD+ nasal spray · 4 min read
- NAD+ Nasal Spray Effectiveness: Does It Really Work Well?Does NAD+ nasal spray work? See what research shows about intranasal NAD+, why human trials are missing and how to judge whether it's worth trying.NAD+ nasal spray · 4 min read
- Does NAD+ Nasal Spray Need to Be Refrigerated? A Quick GuideDoes NAD+ nasal spray need refrigeration? Follow your pharmacy label. Learn general storage tips, travel advice and what to do if a spray gets warm.NAD+ nasal spray · 3 min read
- NAD+ Nasal Spray vs Injection: Which Delivery Method Wins?NAD+ nasal spray or injection? Compare how each is used, side effects, needles, convenience and evidence, and see why neither has been proven better.NAD+ nasal spray · 5 min read
- NAD+ Nasal Spray Prescription: Do You Actually Need One?Do you need a prescription for NAD+ nasal spray? Compounded NAD+ spray from a licensed pharmacy does. Learn why, how to get one online and what to avoid.NAD+ nasal spray · 3 min read
- NAD Nasal Spray vs Pill: Which Option Truly Works Better?NAD+ nasal spray vs pills: compare oral NAD+, NADH, NR and NMN with prescription spray, what human trials show for each and the costs and trade-offs.NAD+ nasal spray · 5 min read
Official sources
NAD+ nasal spray: sources and official resources
Official government and research sources behind this page, so you can check the facts yourself.
- NIH Office of Dietary SupplementsNiacin: Health Professional Fact Sheet
Explains how the body turns niacin (vitamin B3) into NAD, a coenzyme used by more than 400 enzymes.
- NIH PubMed CentralCovarrubias et al. NAD+ metabolism and its roles in cellular processes during ageing (2021)
Review of how NAD+ works in cells and how levels change with age.
- NIH PubMedNAD+ therapy in age-related degenerative disorders: a benefit/risk analysis (2020)
Weighs early promise against the lack of long-term human trials.
- U.S. Food and Drug AdministrationHuman Drug Compounding
FDA's hub on compounding, including that compounded drugs aren't FDA-reviewed for safety or effectiveness.
- U.S. Food and Drug AdministrationCompounding and the FDA: Questions and Answers
What compounded medicines are and why they aren't FDA-approved.
- U.S. Food and Drug AdministrationBeSafeRx: Your Source for Online Pharmacy Information
How to spot a legitimate online pharmacy and avoid unsafe sellers.
- U.S. Food and Drug AdministrationDisposal of Unused Medicines: What You Should Know
Take-back locations and safe ways to get rid of medicine you no longer need.
- U.S. Food and Drug AdministrationMedWatch: The FDA Safety Information and Adverse Event Reporting Program
Where patients can report side effects or problems with a medicine to the FDA.
- U.S. Department of Health and Human ServicesTelehealth for patients
Official guide to how telehealth visits work, what they cost and how to prepare.
Medically reviewed by Dr. Vanessa Niles, R.N., M.D., F.A.C.O.G., on October 12, 2026. This page is general education, not medical advice. NAD+ has no FDA-approved use; compounded NAD+ nasal spray is not FDA-approved and the FDA hasn’t evaluated it for safety or effectiveness. A licensed provider must look over your health and approve it before it’s prescribed, and experiences differ from person to person.
Ready to ask about NAD+ nasal spray?
Book a free online consultation. A licensed provider will tell you honestly whether it suits you.
Book a free consultation