Nasal SprayFrom $166/mo
InjectionFrom $166/mo
Medically reviewed by Vanessa Niles, R.N., M.D., F.A.C.O.G. —
Definition
Compounded medication, in plain English
The FDA describes compounding as combining, mixing or altering ingredients to create a medication tailored to an individual patient's needs.
The FDA doesn't review compounded drugs for safety, effectiveness or quality before they're dispensed. That's why it matters to use a licensed, state-regulated pharmacy and a valid prescription.
- Made by
- Licensed pharmacist
- FDA-approved
- No
- Requires
- A valid prescription (503A)
How it connects
How compounded medication relates to NAD+
There's no FDA-approved NAD+ product. NAD+ nasal sprays and injections in the U.S. are compounded by pharmacies under a prescription.
For your treatment
What compounded medication means for NAD+ therapy
NADMedics works with licensed U.S. pharmacies, and a licensed provider must prescribe NAD+ for you. You can check online pharmacies with the FDA's BeSafeRx resources and NABP's Safe.Pharmacy.
- Free online consultation with a licensed U.S. provider
- NAD+ nasal spray or injection, plans from $166 a month if prescribed
- NAD+ has no FDA-approved use; compounded NAD+ isn’t FDA-approved
Questions
Compounded medication: common questions
What is a compounded medication?
A compounded medication is a drug mixed or altered by a licensed pharmacist for an individual patient. Compounded drugs, including compounded NAD+, aren't FDA-approved.
Why isn't compounded NAD+ FDA-approved?
Compounded drugs made under federal law are exempt from the FDA approval process, so the FDA hasn't evaluated them for safety or effectiveness.
Is compounding legal?
Yes, under sections 503A and 503B of the Federal Food, Drug, and Cosmetic Act, within the limits those laws set.
What strengths does NADMedics prescribe?
Nasal spray: 30 mg per 0.1 mL in a 15 mL bottle. Injection: 200 mg/mL in a 5 mL vial. Your provider sets your dose.
How do I report a side effect?
Tell your provider, and you can report it to the FDA's MedWatch program. Call 911 for chest pain or trouble breathing.
Do I need a prescription for NAD+?
Yes. Compounded NAD+ requires a prescription from a licensed provider after a review of your health.
Keep learning
Related NAD+ terms
Terms that connect to compounded medication, each explained on its own page.
- Treatment & safety503A compounding pharmacyA 503A pharmacy is a state-licensed pharmacy that compounds medicine for individual patients with a valid prescription, under section 503A of federal law. 503B outsourcing facilities work differently.
- MoleculesNAD+NAD+ is the oxidized form of nicotinamide adenine dinucleotide, a coenzyme found in every living cell. It carries electrons for energy metabolism and is used by enzymes involved in DNA repair.
- Treatment & safetySubcutaneous injectionA subcutaneous injection is a shot into the fatty layer just under the skin, usually in the belly or thigh, with a short, thin needle. It's how at-home NAD+ injections are given.
- Treatment & safetyIntranasal administrationIntranasal administration means giving a medicine as a spray into the nose, where it's absorbed through the nasal lining. It's how NAD+ nasal spray is used.
Guides that cover compounded medication
Official sources
Compounded medication: sources and official resources
Official government and research sources behind this page, so you can check the facts yourself.
- U.S. Food and Drug AdministrationCompounding and the FDA: Questions and Answers
What compounded medicines are and why they aren't FDA-approved.
- U.S. Food and Drug AdministrationHuman Drug Compounding
FDA's hub on compounding, including that compounded drugs aren't FDA-reviewed for safety or effectiveness.
- U.S. Food and Drug AdministrationHuman Drug Compounding Laws
How sections 503A and 503B of federal law govern compounding pharmacies and outsourcing facilities.
- U.S. Food and Drug AdministrationBeSafeRx: Your Source for Online Pharmacy Information
How to spot a legitimate online pharmacy and avoid unsafe sellers.
- National Association of Boards of PharmacySafe.Pharmacy
Check whether an online pharmacy is legitimate before you buy.
Medically reviewed by Dr. Vanessa Niles, R.N., M.D., F.A.C.O.G., on October 12, 2026. This glossary is general education, not medical advice. NAD+ has no FDA-approved use, and compounded NAD+ is not FDA-approved or evaluated by the FDA for safety or effectiveness. Talk with a licensed provider before starting any supplement or treatment.
Questions about NAD+? Ask a provider
Book a free online consultation. A licensed U.S. provider reviews your health and, if NAD+ fits, prescribes the nasal spray or injection, with plans from $166 a month.
Book a free consultation